Table 1 Management of women in the English pilot of primary cervical screening with HR-HPV testing

From: 16/18 genotyping in triage of persistent human papillomavirus infections with negative cytology in the English cervical screening pilot

Time of testing

Genotyping triage

Non-genotyping triageb

Baseline test

HR-HPV-negative: routine recall at 3/5 yearsa

HR-HPV-positive/positive cytology: colposcopy

HR-HPV-positive/negative cytology: early recall at 12 months

Early recall at 12 months

HR-HPV-negative: routine recall at 3/5 yearsa

HR-HPV-positive/cytology positive: colposcopy

HPV 16/18-positive/cytology-negative: colposcopy

Other HR-HPV-positive/cytology-negative: early recall at 24 months

HR-HPV-positive/cytology - negative: early recall at 24 months

Early recall at 24 months

HR-HPV-negative: routine recall at 3/5 yearsa

HR-HPV-positive: colposcopy

  1. aDepending on the woman’s age. The 3-year routine recall interval is used for women aged 25–49 years, whereas the 5-year interval is used for women aged 50–64 years.
  2. bOne of the laboratories recorded HR-HPV genotyping information using a DNA assay but did not use it for clinical management of HR-HPV-positive women
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