Table 3 Univariate analysis for overall survival

From: CK7 and consensus molecular subtypes as major prognosticators in V600EBRAF mutated metastatic colorectal cancer

Characteristics

Median OS (months)

Overall survival

HR

95% CI

p

CDX2

 High

22.3

1

–

–

 Intermediate

16

1.72

1.03–2.86

0.036

 Low

12.7

   

CK7

 Low

22.3

1

–

–

 High

7.2

2.17

1.10–4.29

0.026

CK20

 Pos

22

1

–

 

 Neg

9.7

1.75

0.83–3.69

0.14

CMS

 1

26.3

1

–

–

 2–3

19.2

2.7

1.41–5.26

0.003

 4

12.7

   

TILs

 High

22

1

–

–

 Low

13.9

1.72

1.16– 2.56

0.007

BM

 2

22

1

–

–

 1

15.6

1.37

0.87–2.17

0.177

Simplified score

 Low

23.3

1

–

–

 Intermediate

19.5

   

 High

6.6

2.61

1.53–4.48

<0.001

  1. Bold values indicate statistical significance p < 0.05
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