Fig. 2

Waterfall plot for the best percentage change in target lesion size (n = 38). Waterfall plot for the best percentage change in target lesion size is shown for 38 patients who had at least one post-baseline efficacy assessment. The colours indicate type of responses. The dashed line at 20% represents the boundary for determination of progressive disease, and the dashed line at –30% represents the boundary for determination of partial response. *Tumour shrinkage over 30% was observed in this patient, but there were new lesions, so it was judged to be disease progression