Table 2 List of compounds identified in the screening in UMUC3 and J82 human bladder cancer cells

From: Systematic chemical screening identifies disulfiram as a repurposed drug that enhances sensitivity to cisplatin in bladder cancer: a summary of preclinical studies

Compound

UMUC3

J82

CP alone

GC(IC20) + CP

CP alone

GC(IC20) + CP

Bonaphton

0.906

0.074

1.044

0.453

Clioquinol

0.999

0.264

0.85

0.172

Demeclocycline hydrochloride

0.87

0.218

0.962

0.367

Disulfiram

0.99

0.144

1.194

0.464

Fludarabine phosphate

1.005

0.099

0.718

0.088

Furazolidone

1.071

0.393

1.238

0.463

Sulconazole nitrate

1.009

0.323

0.918

0.338

Tyloxapol

0.885

0.203

0.846

0.413

  1. CP compound, GC gemcitabine + cisplatin
  2. Data for CP alone indicate the ratio of OD450 for CP alone to OD450 for vehicle
  3. Data for GC (IC20) + CP indicate the ratio of OD450 for GC + CP to OD450 for GC
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