Table 1 CRCs and polyps in individuals with and without BHD.

From: No evidence for increased prevalence of colorectal carcinoma in 399 Dutch patients with Birt-Hogg-Dubé syndrome

 

FLCNMUT

95% CI

FLCNWT

95% CI

p-value

Individuals with CRC (n)

13 (3.3%)

1.5–5.0%

9 (2.4%)

0.8–3.9%

0.52

Individuals with multiple CRC (n)

1 (0.3%)

 

1 (0.3%)

 

1

Mean age at first CRC

61.3

54.7–67.9

69.8

61.0–78.5

0.09

Diameter of first CRC (mm)

39.8 (n = 11)

27.0–52.6

46.7 (n = 6)

33.9–59.4

0.44

Individuals with at least 1 polyp (n)

47 (11.8%)

8.6–15.0%

22(5.8%)

3.4–8.1%

0.004

Individuals with at least 1 adenoma (n)

38 (9.5%)

6.6–12.4%

19 (5.0%)

2.8–7.2%

0.019

Individuals with at least 1 villous adenoma (n)

1 (0.3%)

 

1 (0.3%)

 

1

Median number of polyps per individual

2 (1–29)

 

2 (1–6)

 

0.64

Mean age at first polyp

59.9

56.9–62.8

60.3

54.1–66.5

0.89

  1. Statistically significant p-values are in bold