Table 1 CRCs and polyps in individuals with and without BHD.
FLCNMUT | 95% CI | FLCNWT | 95% CI | p-value | |
---|---|---|---|---|---|
Individuals with CRC (n) | 13 (3.3%) | 1.5–5.0% | 9 (2.4%) | 0.8–3.9% | 0.52 |
Individuals with multiple CRC (n) | 1 (0.3%) | 1 (0.3%) | 1 | ||
Mean age at first CRC | 61.3 | 54.7–67.9 | 69.8 | 61.0–78.5 | 0.09 |
Diameter of first CRC (mm) | 39.8 (n = 11) | 27.0–52.6 | 46.7 (n = 6) | 33.9–59.4 | 0.44 |
Individuals with at least 1 polyp (n) | 47 (11.8%) | 8.6–15.0% | 22(5.8%) | 3.4–8.1% | 0.004 |
Individuals with at least 1 adenoma (n) | 38 (9.5%) | 6.6–12.4% | 19 (5.0%) | 2.8–7.2% | 0.019 |
Individuals with at least 1 villous adenoma (n) | 1 (0.3%) | 1 (0.3%) | 1 | ||
Median number of polyps per individual | 2 (1–29) | 2 (1–6) | 0.64 | ||
Mean age at first polyp | 59.9 | 56.9–62.8 | 60.3 | 54.1–66.5 | 0.89 |