Table 1 Patient characteristics.

From: Phase 2 study of irinotecan plus cetuximab rechallenge as third-line treatment in KRAS wild-type metastatic colorectal cancer: JACCRO CC-08

Characteristics

N = 34 (%)

Age

Median (years) (range)

64.5

(41–80)

Sex

Male

23

(68)

Female

11

(32)

ECOG PS

0

20

(59)

1

13

(38)

2

1

(3)

Site of primary tumour

Right-sided colona

4

(12)

Left-sided colorectumb

30

(88)

Prior resection of the primary tumour

Yes

25

(74)

No

9

(26)

Metastatic sites

Liver

29

(85)

Lung

14

(41)

Peritoneum

8

(24)

No. of metastatic sites

1

9

(26)

2 or 3

19

(56)

≥4

6

(18)

First-line Tx

Oxaliplatin-based

19

(56)

Irinotecan-based

15

(44)

Best overall response in first-line Tx

CR

0

0

PR

29

(85)

SD

5

(15)

 Second-line Tx

Oxaliplatin-based

15

(44)

Irinotecan-based

19

(56)

Bevacizumab

33

(97)

 Best response in second-line Tx

PR

5

(15)

SD

27

(79)

PD

2

(6)

  1. ECOG Eastern Cooperative Oncology Group, PS performance status, No. number, Tx treatment.
  2. aCaecum, ascending and transverse colon.
  3. bDescending and sigmoid colon and rectum.