Fig. 1: Waterfall plots demonstrating the efficacy of belotecan and topotecan monotherapy in patients with sensitive-relapsed SCLC.

Maximum percentage changes in tumour size (sum of the longest diameters of target-lesions) from baseline, in topotecan (a) and belotecan (b) groups. Colours indicate best overall responses determined from the start of treatment until disease progression/recurrence. p values were obtained from Chi-square tests for comparisons of ORR and DCR between groups.