Table 2 Urinary protein level.
From: Novel urinary protein biomarker panel for early diagnosis of gastric cancer
Training cohort (n = 176) | ||||||
|---|---|---|---|---|---|---|
Univariate analysis | Multivariate analysis | |||||
HC (n = 88) (Median (IQR)) | GC (n = 88) (Median (IQR)) | P | Odds ratio (95% CI) | P | ||
TFF1 | (pg/μg) | 5.4 (3.2–13.8) | 30.7 (10.1–74.5) | <0.001 | 1.033 (1.011–1.055) | 0.003 |
ADAM12 | (pg/μg) | 19.5 (10.3–30.1) | 37.4 (20.0–61.6) | <0.001 | 1.026 (1.009–1.043) | 0.003 |
PGA3 | (pg/μg) | 3.4 (1.0–6.3) | 5.7 (2.3–27.5) | 0.002 | ||
BARD1 | (pg/μg) | 28.3 (17.4–49.6) | 41.5 (27.5–72.2) | 0.003 | ||
CCDC38 | (pg/μg) | 36.1 (20.2–52.3) | 37.5 (25.6–73.7) | 0.162 | ||
TINAGL1 | (pg/μg) | 0.0 (0.0–1.3) | 0.0 (0.0–2.2) | 0.873 | ||
NDRG1 | (pg/μg) | 225 (122–504) | 325 (156–465) | 0.576 | ||
DDX55 | (pg/μg) | 57.1 (31.8–83.8) | 59.3 (37.1–133.1) | 0.089 | ||
H. pylori | <0.001 | 3.717 (1.502–9.259) | 0.005 | |||
Validation cohort (n = 88) | ||||||
|---|---|---|---|---|---|---|
Univariate analysis | Multivariate analysis | |||||
HC (n = 44) (Median (IQR)) | GC (n = 44) (Median (IQR)) | P | Odds ratio (95% CI) | P | ||
TFF1 | (pg/μg) | 9.2 (5.3–18.0) | 54.9 (21.3–93.9) | <0.001 | 1.010 (0.997–1.023) | 0.136 |
ADAM12 | (pg/μg) | 19.7 (12.7–33.5) | 32.5 (22.2–54.8) | 0.002 | 1.034 (1.006–1.064) | 0.018 |
H. pylori | <0.001 | 11.764 (3.472–40.000) | <0.001 | |||
