Table 1 Differences in stage III NSCLC tumour stage classification criteria between the seventh and eighth edition of the tumour, node and metastases classification of lung cancer.

From: The current treatment landscape in the UK for stage III NSCLC

Stage

Seventh edition TNM

Eighth edition TNM

T3

A primary tumour >7 cm

Or a tumour that invades:

• Parietal pleura

• Chest wall

• Phrenic nerve

• Diaphragm

• Mediastinal pleura

• Pericardium

Or a tumour <2 cm from the carina in the main bronchi

Or a tumour causing atelectasis/obstructive pneumonitis of the entire lung

Or a tumour with a separate tumour nodule in the same lobe

A primary tumour >5 cm but ≤7 cm

Or a tumour that invades:

• Parietal pleura

• Chest wall

• Phrenic nerve

• Pericardium

Or a tumour with a separate tumour nodule in the same lobe

T4

A tumour that invades:

• Mediastinum

• Heart

• Great vessels

• Trachea

• Recurrent laryngeal nerve

• Oesophagus

• Vertebral body

• Carina

Or a tumour with a separate tumour nodule in a different ipsilateral lobe

A primary tumour >7 cm

Or a primary tumour that invades:

• Diaphragm

• Mediastinum

• Heart

• Great vessels

• Trachea

• Recurrent laryngeal nerve

• Oesophagus

• Vertebral body

• Carina

Or a tumour with a separate tumour nodule in a different ipsilateral lobe

  1. This table was created by the author using guidance from refs. 44,45