Table 1 Patient demographics.
Characteristic | 1A (dose escalation) N (%) | 1B (dosing adjustment) N (%) | Total N (%) |
|---|---|---|---|
Number of patients | 21 (60) | 14 (40) | 35 (100) |
Age, years, median (range) | 63 (31–78) | 54 (17–74) | 60 (17–78) |
Sex | |||
Female | 9 (43) | 5 (36) | 14 (40) |
Male | 12 (57) | 9 (64) | 21 (60) |
Cancer type | |||
CRPC | 8 (38) | 4 (29) | 12 (34) |
Melanoma | 2 (10) | 3 (21) | 5 (14) |
NMC | 0 (0) | 4 (29) | 4 (11) |
ER + BC | 4 (19) | 0 (0) | 4 (11) |
Other | 7 (33) | 3 (21) | 10 (29) |
ECOG PS | |||
0 | 10 (48) | 3 (21) | 13 (37) |
1 | 11 (52) | 11 (79) | 22 (63) |
≥3 Prior lines of antineoplastic treatment | 19 (90) | 10 (71) | 29 (83) |
