Fig. 5: Volcano plot of the odds ratio per standard deviation from random-effects inverse-variance-weighted (IVW) Mendelian randomisation analysis of the 316 phenotypes with non-GBM risk.
From: Searching for causal relationships of glioma: a phenome-wide Mendelian randomisation study

Top dashed grey line corresponds to a Bonferroni-corrected P value of −log10 P value of 3.80 (P = 1.58 × 10−4), indicating significant association. Bottom dashed grey line corresponds to −log10 P value of 1.30 (P = 0.05) indicating a suggestive association. Vertical dashed grey lines correspond to log (OR = 1.5) and –log (OR = 1.5).