Fig. 5: The role of Rab7a, Rab25 and Rheb prenylation in the resistance to sunitinib in ccRCC cells.

786-O and PNX0010 cells were treated with sunitinib at 10 μM for 24 h. Apoptosis was examined using APO-BRDU kit followed by flow cytometry analysis. Data are presented as the mean ± S.D.