Table 1 Patient, disease and treatment characteristics.
Parameters | Cohort (n = 848) | Percentage (%) |
---|---|---|
Age (median) | 57 years (range: 29–87) | |
Sex | ||
Male | 741 | 87.4 |
Female | 107 | 12.6 |
Smoking status | ||
Never | 364 | 42.9 |
Previous <10 pack years | 97 | 11.4 |
Previous >10 pack years | 215 | 25.3 |
Current | 172 | 20.4 |
Primary site | ||
Base of tongue | 463 | 54.7 |
Tonsil | 368 | 43.4 |
Soft palate | 10 | 1.2 |
Pharyngeal wall | 7 | 0.8 |
Tumour (T) stagea | ||
T1 | 155 | 18.2 |
T2 | 304 | 35.9 |
T3 | 209 | 24.6 |
T4 | 162 | 19.1 |
Tx | 18 | 2.1 |
Nodal (N) stagea | ||
N0 | 41 | 4.8 |
N1 | 74 | 8.7 |
N2a | 51 | 6.0 |
N2b | 423 | 49.8 |
N2c | 211 | 25.0 |
N3 | 45 | 5.3 |
Nx | 3 | 0.4 |
Stage (AJCC Seventh edition)a | ||
II | 11 | 1.3 |
III | 82 | 9.7 |
IV | 755 | 89.0 |
HPV/p16 status | ||
Positive | 602 | 71.0 |
Negative | 71 | 8.4 |
Unknown | 175 | 20.6 |
Dose (median) | 6996 cGy (range: 4800–7396) | |
Number of fractions (median) | 33 (range: 28–42) | |
Induction chemotherapy | ||
Yes | 382 | 45.1 |
No | 466 | 54.9 |
Concurrent chemotherapy | ||
Yes | 742 | 87.5 |
No | 106 | 12.5 |