Table 2 Univariate and multivariate analysis using Cox proportional hazard regression model in PUCH cohort.

From: Development and validation of a novel staging system integrating the number and location of lymph nodes for gastric adenocarcinoma

 

Univariate

Multivariate

Variable

P value

Coefficients

HR

95% CI

P value

Tumour size (cm)

   ≤5 (reference)

<0.001

    

   >5

 Extent of gastrectomy

   Distal (reference)

<0.001

0.323

1.00

 

0.020

   Total

  

1.35

1.05–1.74

 

 Differentiation

   Differentiated (reference)

0.010

    

   Undifferentiated

 Histological type

   Adenocarcinoma (reference)

0.026

    

   Signet ring cell carcinoma

   Mucinous adenocarcinoma

 AJCC pT stage

   T1 (reference)

<0.001

0.593

1.00

 

<0.001

   T2

  

3.78

1.12–12.80

 

   T3

  

8.70

2.72–27.87

 

   T4a

  

12.92

4.08–40.86

 

   T4b

  

28.59

8.50–96.15

 

 TLNs

   ≤30 (reference)

0.005

−0.008

  

0.028

   >30

  

0.74

0.56–0.97

 

  PMLNs

<0.001

0.044

1.04

1.03–1.06

<0.001

  EMLNs

<0.001

0.115

1.12

1.08–1.16

<0.001

  1. AJCC American Joint Committee on Cancer, TLN total number of lymph nodes retrieved, PMLN perigastric metastatic lymph node, EMLN extra-perigastric metastatic lymph node, CI confidence intervals.
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