Fig. 3: Distribution of 21-gene RS among IDC/DCIS patients.

a In all, 21-gene RS as a categorical variable in patients with different DCIS grades (chi-square test P < 0.001); b 21-gene RS as a continuous variable in patients with different DCIS grades (Kruskal–Wallis test P < 0.001); c 21-gene RS as a categorical variable in patients with different proportions of DCIS (chi-square test P = 0.057); d 21-gene RS as a continuous variable in patients with different proportions of DCIS (Mann–Whitney test P = 0.064).