Fig. 5: Hyperpolarised 13C-MRI on a patient with pancreatic cancer.
From: The use of hyperpolarised 13C-MRI in clinical body imaging to probe cancer metabolism
Top row: anatomical axial slice showing the pancreatic tumour (white arrow) and the exocrine pancreas (purple arrow); the green region of interest outlines the whole pancreas. The ADC is greatly reduced in the tumour tissue. Bottom row: high [1‐13C]pyruvate, [1‐13C]lactate and [1‐13C]alanine signals were observed in the pancreatic tumour, with images acquired >30 sec after injection of hyperpolarised [1‐13C]pyruvate. The spectrum acquired in the area of the pancreatic cancer shows [1‐13C]pyruvate, [1‐13C]lactate and [1‐13C]alanine peaks. Reprinted from50 with permission from John Wiley & Sons.
