Table 1 Characteristics of the osteosarcoma and ewing sarcoma cohorts.
Osteosarcoma | Ewing sarcoma | Total | |||||
---|---|---|---|---|---|---|---|
No. of patients | 1201 | 578 | 1779 | ||||
Sex | |||||||
Male | 705 (59%) | 358 (62%) | 1063 (60%) | ||||
Female | 496 (41%) | 220 (38%) | 716 (40%) | ||||
Age at diagnosisa | 21.8 (15.3–54.9) | 17.4 (12–23.2) | 19.4 (14.3–40.9) | ||||
0–9 years | 87 (7%) | 104 (18%) | 188 (11%) | ||||
10–19 years | 471 (39%) | 273 (47%) | 744 (42%) | ||||
≥20 years | 646 (54%) | 201 (35%) | 847 (48%) | ||||
Calendar year at diagnosis | |||||||
1958–1979 | 474 (40%) | 167 (29%) | 641 (36%) | ||||
1980–1999 | 399 (33%) | 214 (37%) | 613 (35%) | ||||
2000–2015 | 328 (27%) | 197 (34%) | 525 (30%) | ||||
Site | |||||||
Extremity | 979 (82%) | 304 (53%) | 1283 (72%) | ||||
Unspecified | 41 (3%) | 24 (4%) | 65 (4%) | ||||
Central | 181 (15%) | 250 (43%) | 431 (24%) | ||||
Spineb | 26 (14%) | 31 (12%) | 57 (13%) | ||||
Pelvicb | 104 (58%) | 136 (54%) | 24 (56%) | ||||
Tissue | |||||||
Bone | 1135 (95%) | 495 (86%) | 1630 (92%) | ||||
Soft tissue | 66 (5%) | 83 (14%) | 149 (8%) | ||||
Malignancy prior to primary bone cancer | 79 (7%) | 7 (1%) | 86 (5%) | ||||
Follow-up (years)a | 2.5 (0–57.8) | 2.9 (0–56.3) | 2.6 (0–57.8) | ||||
Time to SPN (years)a | 17.1 (0–52.8) | 17.0 (0−48.7) | 17.1 (0–52.8) |