Fig. 1: Selection of immune features by LASSO Cox analysis in hepatocellular carcinoma (HCC) patients with early stage.

a Immunohistochemistry (IHC) staining of selected prognostic features expression in four HCC patients (#27, #40, #63, and #139), including CD27T, CD57T, CD57P, CD45RAP, CD45ROT, CD66bT, CD68P, CXCR5P, and PD-1T (T represents tumoural, P represents peritumoural). Bar, 20āμm. b Comparison of positive immune cells in intratumoural and peritumoural tissues in IHC analysis by t test analysis. c The two dotted vertical lines were drawn at the optimal values by minimum criteria (right) and 1-s.e. criteria (left). d LASSO coefficient profiles of the 28 features. **Pā<ā0.01, ***Pā<ā0.001, and ****Pā<ā0.0001.