Table 1 Demographic, clinical, and tumour characteristics of patients with hepatocellular carcinoma.

From: Nine-factor-based immunohistochemistry classifier predicts recurrence for early-stage hepatocellular carcinoma after curative resection

Patient demographics

Training cohort (n = 195)

Testing cohort (n = 114)

Validation cohort (n = 355)

P value

Age, years

Ā ā€ƒ<60

150

88

263

0.68

Ā ā€ƒā‰„60

45

26

92

Ā 

Ā Sex (male), n (%)

158 (81.0%)

96 (84.2%)

306 (86.2%)

0.28

Ā HBV

163

95

298

0.51

Ā Liver cirrhosis, yes (%)

155 (79.5%)

89 (78.1%)

302 (85.1%)

0.12

Ā AFP, ng/ml

76.0 (6.0, 807.0)

120.5 (5.3, 675.0)

77.0 (5.0, 861.5)

0.86

Ā Albumin, g/dl

4.2 (3.9, 4.6)

4.4 (4.1, 4.6)

4.4 (4.0, 4.7)

0.02

 Bilirubin, μmol/l

15.1 (11.9, 19.0)

15.0 (11.7, 19.4)

14.1 (10.5, 18.4)

0.05

Ā ALT, IU/l

41.0 (27.5, 67.5)

41.0 (27.5, 57.5)

38.0 (26.0, 52.0)

0.10

Ā GGT, U/l

53.0 (34.0, 100.0)

50.0 (30.3, 95.5)

57.0 (37.0, 99.0)

0.22

Ā Tumour diameter, cm

4.0 (2.5, 6.0)

4.0 (2.5, 7.0)

3.5 (2.5, 6.0)

0.41

Ā Microvascular invasion (yes), n (%)

62 (31.8%)

32 (28.1%)

98 (27.6%)

0.57

Tumour differentiation

Ā ā€ƒI–II

147

87

253

0.42

Ā ā€ƒIII–IV

48

27

102

Ā 

CGLC stage

Ā Ā Ā 

0.30

Ā ā€ƒIa

128

76

254

Ā 

Ā ā€ƒIb

67

38

101

Ā 

BCLC

Ā ā€ƒ0

29

13

46

0.67

Ā ā€ƒA

166

101

309

Ā 
  1. Values are presented as no. (%) or median (Q1, Q3).
  2. HBV hepatitis B virus, AFP α-fetoprotein, ALT alanine aminotransferase, GGT γ-glutamyl transpeptidase, CGLC China Guideline for Liver Cancer, BCLC Barcelona Clinic Liver Cancer.