Fig. 3: Sensitivity and specificity of longitudinal CTC and EBV DNA assays in mNPC.

a Summary of AUROC, sensitivity, specificity, positive and negative predictive values (PPV and NPV) of CTCs and EBV DNA load for PFS in mNPC. b ROC analysis to test the specificity and sensitivity of CTC4, EBV4, combined CTC4/EBV4 and CTC4/EBV4/BML for PFS in mNPC patients with favourable response.