Table 1 Baseline characteristics.

From: Association of tumour and stroma PD-1, PD-L1, CD3, CD4 and CD8 expression with DCB and OS to nivolumab treatment in NSCLC patients pre-treated with chemotherapy

Ā 

Derivation, n (%)

Validation, n (%)

p value

Number of patients

69

70

Ā 

Mean age in years, mean ± SD

62.3 ± 10.7

63.7 ± 7.2

0.37

Number of biopsy samples

69

70

0.87

Ā Obtained after the last line of treatment (ACT)

36 (52.2)

35 (50.0)

Ā 

Ā Obtained before the last line of treatment (BCT)

33 (47.8)

35 (50.0)

Ā 

Sex

Ā Ā 

0.61

Ā Male

40 (58.0)

37 (52.9)

Ā 

Ā Female

29 (42.0)

33 (47.1)

Ā 

Histological subtypes

Ā Ā 

0.31

Ā Squamous

20 (29.0)

21 (68.6)

Ā 

Ā Nonsquamous

46 (66.7)

48 (30.0)

Ā 

Ā Other (adenosquamous, LCNEC, NOS or unknown)

3 (4.3)

1 (1.4)

Ā 

ECOG performance score

Ā Ā 

0.59

Ā 0

7 (10.1)

8 (11.4)

Ā 

Ā 1

44 (63.8)

40 (57.1)

Ā 

 ≄2

16 (23.2)

22 (31.4)

Ā 

Ā Unknown

2 (2.9)

0 (0)

Ā 

DCB rate

Ā Ā 

0.34

Ā Patients without DCB

15 (21.7)

21 (30.0)

Ā 

Ā Patients with DCB

54 (78.3)

50 (70.0)

Ā