Table 5 Multivariate analysis for biopsies taken after the last line of therapy (ACT).

Tumour PD-L1 expression

0.047

 <1% (n = 47)

23

1.0

 1–50% (n = 9)

22

0.78 (0.13–4.8)

 ≥50% (n = 13)

69

6.5 (1.4–30.7)

Combined tumour and stromal infiltration of CD8⁺ IC

0.012

 Low infiltration of tumour and stromal CD8⁺ IC (n = 31)

19

1.0

 High infiltration of tumour or stromal CD8⁺ IC (n = 11)

9

0.29 (0.026–3.1)

 High infiltration of tumour and stromal CD8⁺ IC (n = 28)

54

4.5 (1.3–15.9)