Table 4 Multivariate Cox regression analysis.
From: Early treatment-related neutropenia predicts response to palbociclib
Covariate | HR (95% CI) | p Value |
|---|---|---|
All patients | ||
Any NTP in C1–2 | ||
No | ||
Yes | 0.49 (0.34–0.70) | <0.001 |
ECOG PS | ||
0 | ||
1 | 1.51 (1.12–2.04) | 0.007 |
# Prior lines of therapy | ||
1–2 | ||
3+ | 1.39 (1.02–1.87) | 0.033 |
Breast patients | ||
Any NTP in C1–2 | ||
No | ||
Yes | 0.19 (0.07–0.52) | 0.001 |
Age | ||
<Median | ||
≥Median | 0.50 (0.29–0.89) | 0.017 |
Immediate prior line chemo | ||
No | ||
Yes | 1.76 (1.02–3.03) | 0.042 |
Non-breast patients | ||
Any NTP in C1–2 | ||
No | ||
Yes | 0.56 (0.37–0.83) | 0.004 |
ECOG PS | ||
0 | ||
1 | 1.68 (1.15–2.43) | 0.006 |
# Prior lines of therapy | ||
1–2 | ||
3+ | 1.81 (1.22–2.70) | 0.003 |
