Fig. 6: Overall survival in GOA patients with metastatic disease and a trackable SNV.

a ROC curve to determine best cut-off point for OS less than 6 months. Using ctDNA levels (copies/ml) at diagnosis of metastatic disease. b Kaplan–Meier plot showing the OS for metastatic/relapse patients based on initial ctDNA levels (dichotomised by ROC-determined cut-off value). Censored: still alive at the end of follow-up.