Fig. 5: ETNK2 mRNA expression in clinical GC tissues is significantly associated with hepatic recurrence and prognosis. | British Journal of Cancer

Fig. 5: ETNK2 mRNA expression in clinical GC tissues is significantly associated with hepatic recurrence and prognosis.

From: Hepatic metastasis of gastric cancer is associated with enhanced expression of ethanolamine kinase 2 via the p53–Bcl-2 intrinsic apoptosis pathway

Fig. 5

a qRT-PCR analysis of ETNK2 mRNA levels in normal and GC tissues from patients in our institutional cohort according to disease stage. b Kaplan–Meier overall survival curves for patients with Stage I–IV GC in the institutional and validation cohorts. c Cumulative incidence of hepatic and peritoneal recurrence in patients with Stage I–III GC in the institutional cohort. d IHC staining of GC specimens from patients in our institutional cohort. Left panels show representative images of tissues categorised as negative, weak, and strong staining for ETNK2 protein. Right panel shows ETNK2 expression in patients with and without haematogenous recurrence (n = 88). Data in a are presented as the mean ± standard deviation.

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