Table 3 Correlations between the soluble cluster of differentiation molecule 40 and other circulating factors—all cohorts.

From: The circulating soluble form of the CD40 costimulatory immune checkpoint receptor and liver metastasis risk in rectal cancer

 

N (%)

Spearman’s rho

P

Pa

CXCL2

260 (66)

0.042

0.501

0.872

ANGPT2

395 (100)

0.083

0.100

0.403

TNFRSF10B

201 (51)

0.359

<0.001

<0.001

FLT3LG

245 (62)

0.345

<0.001

<0.001

VEGFA

180 (46)

–0.047

0.533

0.872

IL-6

164 (42)

0.296

<0.001

<0.001

TNF-α

177 (45)

0.125

0.098

0.403

IFN-γ

176 (45)

–0.052

0.496

0.872

Haemoglobin

334 (85)

–0.219

<0.001

<0.001

Thrombocytes

316 (80)

0.082

0.147

0.493

Neutrophils

300 (76)

0.093

0.107

0.493

Lymphocytes

298 (75)

–0.056

0.333

0.568

Monocytes

297 (75)

0.186

0.001

0.013

C-reactive protein

301 (76)

0.185

0.001

0.013

Albumin

315 (80)

–0.187

0.001

0.013

Carcinoembryonic antigen

333 (84)

0.163

0.003

0.027

Erythrocyte sedimentation rate

120 (30)

0.501

<0.001

<0.001

Creatinine

180 (46)

0.077

0.302

0.568

Aspartate aminotransferase

214 (54)

–0.139

0.042

0.291

Alanine aminotransferase

322 (82)

–0.235

<0.001

<0.001

Lactate dehydrogenase

283 (72)

0.193

0.001

0.013

Alkaline phosphatase

319 (81)

0.065

0.244

0.568

γ-glutamyl transferase

296 (75)

0.103

0.078

0.434

Bilirubin

318 (81)

–0.090

0.109

0.493

  1. ANGPT2 angiopoietin-2, CXCL2 C–X-C motif chemokine ligand 2, FLT3LG fms-related receptor tyrosine kinase 3 ligand, IFN-γ interferon γ, IL-6 interleukin-6, TNF-α tumour necrosis factor α, TNFRSF10B TNF superfamily member 10B, VEGFA vascular endothelial growth factor A.
  2. aCorrected for multiple comparisons.
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