Table 2 Relationship between chemotherapy use and patient characteristics: univariate (Table 2a) and multi-variable (Table 2b) analyses.
(a) Results for univariate logistic regression models. | |||
|---|---|---|---|
Variable | Level | OR (95% CI) | P-value |
Age | 0.84 (0.82, 0.87) | <0.001 | |
ADL score | 1.07 (1.04, 1.11) | <0.001 | |
IADL score | 1.77 (1.43, 2.25) | <0.001 | |
CCI (no age) | 0.84 (0.77, 0.93) | <0.001 | |
APG-SGA | 0.95 (0.89, 1.01) | 0.127 | |
Allred score | 0.80 (0.78, 0.83) | <0.001 | |
Tumour grade | Grade 1 | – | – |
Grade 2 | 9.04 (3.78, 29.58) | <0.001 | |
Grade 3 | 37.67 (15.87, 122.76) | <0.001 | |
ER positive | 0.22 (0.17, 0.28) | <0.001 | |
HER2 statusa | Negative | – | – |
Positive | 8.49 (6.57, 10.97) | <0.001 | |
MMSE category | Normal function | – | – |
Mild impairment | 0.75 (0.49, 1.11) | 0.172 | |
Moderate impairment | 1.18 (0.44, 2.67) | 0.711 | |
Severe | 0.38 (0.06, 1.27) | 0.188 | |
Nodal statusb | pN0-1mi | – | – |
pN1 | 2.18 (1.69, 2.80) | <0.001 | |
pN2 | 5.05 (3.47, 7.29) | <0.001 | |
pN3 | 6.42 (3.96, 10.30) | <0.001 | |
(b) Results from the multi-variable logistic regression model. | |||
|---|---|---|---|
Variable | Level | OR (95% CI) | P-value |
Age | 0.74 (0.71, 0.78) | <0.001 | |
IADL score | 1.97 (1.53, 2.63) | <0.001 | |
CCI (no age) | 0.83 (0.73, 0.95) | 0.007 | |
Tumour grade | Grade 1 | – | – |
Grade 2 | 8.42 (3.05, 34.90) | <0.001 | |
Grade 3 | 29.50 (10.59, 123.00) | <0.001 | |
ER positive | 0.19 (0.13, 0.28) | <0.001 | |
HER2 status | Negative | – | – |
Positive | 8.94 (6.19, 13.01) | <0.001 | |
Nodal status | pN0-1mi | ||
pN1 | 4.01 (2.81, 5.75) | <0.001 | |
pN2 | 11.24 (6.43, 19.74) | <0.001 | |
pN3 | 8.84 (4.31, 18.05) | <0.001 | |
