Table 4 Associations of all cancers, screen-detected, interval, node-negative, node-positive and combined (node-positive or interval) cancers with continuous breast density measures.
Mean | Mean | Difference | CI | p-value | AUC | 95% CIa | p-valueb | |
|---|---|---|---|---|---|---|---|---|
Controls | All cancers | p < 0.01 | ||||||
FGV (cm3) | 53.7 | 66.3 | 12.6 | (8.1, 17.1) | p < 0.01 | 0.63 | (0.59, 0.67) | |
VBD (%) | 8.2 | 9.2 | 1.0 | (0.3, 1.7) | p < 0.01 | 0.56 | (0.51, 0.60) | |
VAS (%) | 44.4 | 48.2 | 3.8 | (1.3, 6.4) | p < 0.01 | 0.55 | (0.51, 0.59) | |
Controls | Screen-detected | p < 0.01 | ||||||
FGV (cm3) | 53.7 | 64.4 | 10.8 | (5.0, 16.5) | p < 0.01 | 0.61 | (0.56, 0.66) | |
VBD (%) | 8.2 | 8.1 | −0.1 | (−0.9, 0.8) | p = 0.87 | 0.51 | (0.46, 0.56) | |
VAS (%) | 44.4 | 44.1 | −0.3 | (−3.3, 2.7) | p = 0.84 | 0.50 | (0.46, 0.55) | |
Controls | Interval cancers | p = 0.06 | ||||||
FGV (cm3) | 53.7 | 68.2 | 14.5 | (8.9, 20.1) | p < 0.01 | 0.65 | (0.60, 0.70) | |
VBD (%) | 8.2 | 10.3 | 2.1 | (1.2, 3.0) | p < 0.01 | 0.63 | (0.58, 0.68) | |
VAS (%) | 44.4 | 52.4 | 8.1 | (5.0, 11.1) | p < 0.01 | 0.60 | (0.56, 0.65) | |
Controls | Node-negative cancers | p < 0.01 | ||||||
FGV (cm3) | 53.7 | 64.1 | 10.4 | (5.8, 15.0) | p < 0.01 | 0.62 | (0.58, 0.67) | |
VBD (%) | 8.2 | 8.8 | 0.6 | (−0.2, 1.4) | p = 0.13 | 0.54 | (0.49, 0.59) | |
VAS (%) | 44.4 | 47.5 | 3.1 | (0.2, 6.0) | p = 0.04 | 0.54 | (0.50, 0.58) | |
Controls | Node-positive cancers | p < 0.01 | ||||||
FGV (cm3) | 53.7 | 71.7 | 18.0 | (9.5, 26.4) | p < 0.01 | 0.65 | (0.59, 0.71) | |
VBD (%) | 8.2 | 10.1 | 1.9 | (0.7, 3.1) | p < 0.01 | 0.60 | (0.54, 0.66) | |
VAS (%) | 44.4 | 49.3 | 4.9 | (1.6, 8.2) | p < 0.01 | 0.56 | (0.51, 0.61) | |
Controls | Combined | p < 0.05 | ||||||
FGV (cm3) | 53.7 | 69.2 | 15.5 | (9.8, 21.2) | p < 0.01 | 0.65 | (0.60, 0.69) | |
VBD (%) | 8.2 | 10.0 | 1.8 | (0.9, 2.7) | p < 0.01 | 0.61 | (0.56, 0.66) | |
VAS (%) | 44.4 | 50.5 | 6.2 | (3.4, 9.0) | p < 0.01 | 0.58 | (0.54, 0.62) |
