Table 3 Bias and uncertainty results from MC simulations for 1C2K and 2C4K ground truths.

From: Characterising 18F-fluciclovine uptake in breast cancer through the use of dynamic PET/CT imaging

Model fitted

Fitted model parameters

Ground-truth 1C2K model

1C2K

vB

K1

k2

  

K1/k2

 MB

–8%

–3%

–3%

  

0.3%

 σ(B)

65%

7%

8%

  

3%

 σ(P)

38%

7%

18%

  

18%

 σ(T)

75%

9%

20%

  

18%

2C4K

vB

K1

k2

k3

k4

K1/k2

 MB

–12%

–

–

–

–

–

 σ(B)

66%

–

–

–

–

–

 σ(P)

35%

9%

57%

56%

91%

52%

 σ(T)

75%

–

–

–

–

–

Ground-truth 2C4K model

1C2K

vB

K1

k2

  

K1/k2

 MB

64%

–

–

  

–

 σ(B)

104%

–

–

  

–

 σ(P)

40%

5%

11%

  

15%

 σ(T)

111%

–

–

  

–

2C4K

vB

K1

k2

k3

k4

K1/k2

 MB

21%

–5%

–14%

–36%

–34%

–1%

 σ(B)

76%

13%

142%

170%

80%

36%

 σ(P)

58%

13%

86%

112%

131%

79%

 σ(T)

96%

18%

166%

203%

153%

87%

  1. Values of MB, σB, σP and σT are shown for fitted parameters. σP is shown alone when no directly related parameter exists. Values are shown as % of the mean fitted parameter value.