Fig. 3: Forest plot showing disease-free survival with anthracycline-free or anthracycline-containing chemotherapy according to the different patient and tumour characteristic subgroups.

Forest plot showing results of explorative subgroup analyses in terms of the comparison of disease-free survival between patients with anthracycline-free or anthracycline-containing chemotherapy according to the different patient and tumour characteristic subgroups. The diamonds indicate the hazard ratios (anthracycline-free vs. anthracycline-containing chemotherapy), and diamond size is proportional to the number of patients per subgroup. The horizontal lines indicate the corresponding 95% confidence intervals for the hazard ratios. The solid vertical line represents a hazard ratio of 1.0 (i.e., no difference in survival between anthracycline-free or anthracycline-containing chemotherapy), and the dashed vertical line represents the hazard ratio for the overall analysis with all 5924 patients (hazard ratio 1.049).