Fig. 2: LHX2 promotes NPC cell growth in vitro and in vivo.
From: LHX2 facilitates the progression of nasopharyngeal carcinoma via activation of the FGF1/FGFR axis
a Western blot analysis of LHX2 protein expression in HONE1 and SUNE1 cells stably overexpressing LHX2. Each experiment was independently repeated at least three times. b The CCK-8 assay and c the colony-formation assay of HONE1 and SUNE1 cells stably overexpressing LHX2. Each experiment was independently repeated at least three times. d Western blot analysis of LHX2 protein expression in HONE1 and SUNE1 cells transfected with LHX2 shRNAs or control cells. Each experiment was independently repeated at least three times. e The CCK-8 assay and f the colony-formation assay of HONE1 and SUNE1 cells transfected with LHX2 shRNAs or control. Each experiment was independently repeated at least three times. g, h Images of Xenograft tumours of nude mice 30 days after injecting with HONE1 and SUNE1 cells stably overexpressing LHX2 or vector (n = 5 in each group). i Tumour volume growth curves. j Average xenograft tumour weights. k Immunohistochemistry assay of LHX2 and Ki67 protein expression in xenograft tumours. Data shown as mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001.
