Fig. 2: Distribution of total and stromal inflammatory cell infiltrates in intraductal papillary neoplasms of the biliary tract (IPN), their associated invasive BTC (INV) and non-tumorous tissue (NT).
From: Spatiotemporal analysis of tumour-infiltrating immune cells in biliary carcinogenesis
a–h Total and stromal counts of a CD3+ T lymphocytes (NT: n = 56; IPN: n = 65; INV: n = 41), b CD4+ T lymphocytes (NT: n = 57; IPN: n = 65; INV: n = 41), c CD8+ T lymphocytes (NT: n = 57; IPN: n = 65; INV: n = 41), d CD20+ B lymphocytes (NT: n = 60; IPN: n = 65; INV: n = 43), e MUM1+ plasma cells (NT: n = 59; IPN: n = 65; INV: n = 42), f CD68+ macrophages (NT: n = 58; IPN: n = 65; INV: n = 42), g CD163+ macrophages (NT: n = 56; IPN: n = 65; INV: n = 42) and h CD56+ NK cells (NT: n = 57; IPN: n = 65; INV: n = 44). Significant P values of Kruskal–Wallis test are shown in bold, followed by Dunn’s post hoc analysis. *P < 0.05, **P < 0.01, ***P < 0.001; ns not significant, NA not applicable.
