Fig. 3: Distribution of intraepithelial inflammatory cell infiltrates in intraductal papillary neoplasms of the biliary tract (IPN), their associated invasive BTC (INV) and non-tumorous tissue (NT).
From: Spatiotemporal analysis of tumour-infiltrating immune cells in biliary carcinogenesis
a Percentage of cases showing any positive intraepithelial inflammatory cells in NT, IPN and INV. Significant P values of Pearson’s chi-squared test are shown in bold. b–d Proportion per 100 biliary epithelial cells of intraepithelial, b CD3+ T lymphocytes, c CD4+ T lymphocytes, d CD8+ T lymphocytes. Significant P values of Kruskal–Wallis test are shown in bold, followed by Dunn’s post hoc analysis. e Spearman’s correlation between all assessed inflammatory parameters in intraductal papillary lesions (IPN). Significant correlations were marked with asterisks: *P < 0.05; **P < 0.01; ***P < 0.001; ns not significant, NA not applicable.
