Fig. 4: The CPT score represents immunogenic microenvironment in MIBC. | British Journal of Cancer

Fig. 4: The CPT score represents immunogenic microenvironment in MIBC.

From: Integrative tumour mutation burden with CD39 and PD-L1 for the prediction of response to PD-L1 blockade and adjuvant chemotherapy in muscle-invasive bladder cancer patients

Fig. 4

a Non-parametric two-sided Spearman correlation analysis was performed to figure out the correlations between CD39+ cells infiltration and CD8+ cells infiltration in ZSHS cohort. b Association between CD39+ cells infiltration and immunotypes in ZSHS cohort. Kruskal–Wallis test was performed (*P < 0.05). c Association between CD39+ cells infiltration and tertiary lymphoid structures in ZSHS cohort. Mann–Whitney U-test was performed. d Heatmap depicting the correlation of CPT score with immune indicators in IMvigor210 cohort. Chi-square test was performed for TCGA subtype and immune phenotype (**P < 0.01; ***P < 0.001). Kruskal–Wallis test was performed for signatures and pathway scores (***P < 0.001). TLS tertiary lymphoid structure.

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