Table 2 Associations of lead mammography radiomics features at diagnosis with invasive disease-free survival among patients with breast cancera, after multiple testing correlation.

From: Mammography radiomics features at diagnosis and progression-free survival among patients with breast cancer

Features

Mean (SD)

Model 1b

Model 2c

Model 3d

 

Controls

Cases

OR (95% CI)

P

OR (95% CI)

P

OR (95% CI)

P

S(1,-1)SumAverg

0.13 (0.95)

−0.13 (1.03)

0.76 (0.56–0.96)

0.043

0.71 (0.50–0.93)

0.035

0.64 (0.42–0.87)

0.010

S(2,0)SumAverg

0.14 (0.97)

−0.14 (1.01)

0.76 (0.55–0.96)

0.043

0.72 (0.51–0.92)

0.035

0.66 (0.44–0.88)

0.010

S(2,−2)SumAverg

0.16 (1.00)

−0.16 (0.98)

0.72 (0.52–0.93)

0.043

0.68 (0.47–0.89)

0.016

0.64 (0.41–0.87)

0.010

S(3,0)SumAverg

0.14 (1.00)

−0.14 (0.98)

0.74 (0.54–0.94)

0.043

0.70 (0.49–0.91)

0.023

0.66 (0.44–0.88)

0.010

S(3,−3)SumAverg

0.16 (1.01)

−0.16 (0.97)

0.72 (0.52–0.92)

0.043

0.68 (0.47–0.89)

0.014

0.65 (0.42–0.87)

0.010

S(4,−4)SumAverg

0.16 (1.01)

−0.16 (0.96)

0.72 (0.51–0.92)

0.043

0.68 (0.47–0.89)

0.014

0.65 (0.43–0.88)

0.010

S(5,−5)SumAverg

0.16 (1.02)

−0.16 (0.96)

0.72 (0.52–0.92)

0.043

0.68 (0.47–0.89)

0.014

0.66 (0.43–0.88)

0.010

WavEnLL_s-6

−0.19 (1.05)

0.19 (0.91)

1.49 (1.28–1.69)

0.026

1.56 (1.35–1.77)

0.011

1.53 (1.31–1.76)

0.010

S(4,0)SumAverg

0.15 (1.01)

−0.15 (0.97)

0.74 (0.54–0.94)

0.043

0.70 (0.49–0.91)

0.020

0.67 (0.44–0.89)

0.011

S(1,0)SumAverg

0.11 (0.92)

−0.11 (1.07)

0.80 (0.60–1.00)

0.062

0.76 (0.55–0.96)

0.066

0.67 (0.45–0.89)

0.012

S(5,0)SumAverg

0.15 (1.02)

−0.15 (0.96)

0.74 (0.54–0.94)

0.043

0.70 (0.49–0.91)

0.020

0.67 (0.45–0.89)

0.012

WavEnLL_s-7

−0.15 (1.04)

0.15 (0.94)

1.36 (1.16–1.55)

0.043

1.43 (1.22–1.63)

0.020

1.48 (1.25–1.70)

0.017

WavEnLL_s-5

−0.18 (1.05)

0.18 (0.92)

1.45 (1.25–1.66)

0.026

1.51 (1.30–1.72)

0.011

1.48 (1.25–1.70)

0.018

WavEnHL_s-5

0.19 (1.02)

−0.19 (0.95)

0.66 (0.43–0.88)

0.026

0.64 (0.41–0.87)

0.011

0.69 (0.46–0.92)

0.028

WavEnLL_s-4

−0.18 (1.05)

0.18 (0.91)

1.46 (1.25–1.66)

0.026

1.50 (1.29–1.71)

0.011

1.44 (1.22–1.67)

0.031

  1. SD standard deviation, OR odds ratio, CI confidence interval.
  2. aOnly features with FDR-corrected P-values less than 0.05 in Model 3 were present.
  3. bCrude model.
  4. cEstimates were adjusted for age and menopausal status.
  5. dEstimates were adjusted for age, menopausal status, molecular subtype, tumour stage and histologic grade.
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