Table 3 Association of stratified GMNN expression and OS, by histotype (n = 5470).
Histotype | Expression | na | 5-year survival (% ± SE) | HR (95% CI)b | p value |
|---|---|---|---|---|---|
HGSC | 0% | 276 | 38.4 ± 3.1 | Ref. | 0.001* |
5% | 870 | 38.6 ± 1.7 | 1.10 (0.94–1.31) | ||
10–15% | 1523 | 38.3 ± 1.3 | 1.07 (0.91–1.26) | ||
20–25% | 1034 | 39.7 ± 1.6 | 0.94 (0.79–1.11) | ||
30% | 206 | 36.5 ± 3.5 | 1.0 (0.80–1.25) | ||
35–100% | 276 | 46.1 ± 3.2 | 0.80 (0.65–1.00) | ||
LGSC | 0% | 46 | 57.2 ± 8.3 | Ref. | 0.126 |
5% | 78 | 61.9 ± 6.0 | 0.91 (0.50–1.65) | ||
10–15% | 27 | 60.2 ± 10.3 | 1.23 (0.52–2.88) | ||
20–25% | 7 | 71.4 ± 17.1 | 2.50 (0.91–6.84) | ||
30% | 2 | N/A | 8.28 (1.36–50.43)* | ||
35–100% | N/A | N/A | N/A | ||
MC | 0% | 31 | 77.3 ± 8.9 | Ref. | 0.89 |
5% | 67 | 62.8 ± 7.3 | 1.52 (0.61–3.80) | ||
10–15% | 56 | 74.5 ± 6.4 | 1.21 (0.47–3.14) | ||
20–25% | 18 | 47.9 ± 12.8 | 1.68 (0.58–4.86) | ||
30% | 1 | 100.0 ± 0.0 | N/A | ||
35–100% | 1 | 100.0 ± 0.0 | N/A | ||
EC | 0% | 80 | 86.0 ± 5.1 | Ref. | 0.1 |
5% | 210 | 87.2 ± 2.6 | 0.81 (0.44–1.49) | ||
10–15% | 162 | 81.8 ± 3.4 | 0.89 (0.47–1.68) | ||
20–25% | 54 | 62.3 ± 7.0 | 1.71 (0.83–3.53) | ||
30% | 4 | 25.0 ± 25.0 | 3.84 (0.96–15.32) | ||
35–100% | 8 | 57.1 ± 18.7 | 1.21 (0.24–6.09) | ||
CCC | 0% | 105 | 69.1 ± 5.7 | Ref. | 0.64 |
5% | 176 | 67.6 ± 3.8 | 0.94 (0.58–1.53) | ||
10–15% | 106 | 67.6 ± 4.8 | 0.86 (0.50–1.48) | ||
20–25% | 33 | 51.5 ± 9.2 | 1.10 (0.55–2.17) | ||
30% | 3 | 66.7 ± 27.2 | 2.62 (0.61–11.17) | ||
35–100% | 10 | 57.4 ± 16.0 | 0.62 (0.22–1.73) |
