Fig. 1: Illustration of intratumoral heterogeneity of Ki67 expression and tumor regression in the examplary case (Supplemental Fig. 1). | British Journal of Cancer

Fig. 1: Illustration of intratumoral heterogeneity of Ki67 expression and tumor regression in the examplary case (Supplemental Fig. 1).

From: Intratumoral heterogeneity affects tumor regression and Ki67 proliferation index in perioperatively treated gastric carcinoma

Fig. 1

Each row represents a seperate block of the same tumor. Tumor regression was evaluated as the ratio of residual (pan-cytokeratin) to former (Masson’s trichrome stain) tumor site. With increasing tumor regression, the hot spot Ki67 PI (KiH) decreased while the Ki67 PI at the lower proliferation end (KiL) increased (values in Supplemental Fig. 1). Ki67 images in 200-fold.

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