Fig. 2: Expression of MSH6, MSH2, PMS2 and MLH1 is prognostic in preoperative lesions.

High individual expression of MSH6, MSH2, PMS2 and MLH1 in curettage was associated with poor disease-specific survival (a–d). Cut-offs determined by Youden Index. P values are given by log-rank (Mantel–Cox) analysis. Number in brackets indicates the total number of patients/number of events. Abbreviations: MutS Homolog 6 (MSH6), MutS Homolog 2 (MSH2), PMS2 Homolog 2 (PMS2), MutL Homolog 1 (MLH1).