Table 1 MMR protein loss/intact expression detected at similar frequencies in curettage and hysterectomy series.
MutSα | MutLα | |||||||
---|---|---|---|---|---|---|---|---|
MSH6 | MSH2 | PMS2 | MLH1 | |||||
Intact (%) | Loss (%) | Intact (%) | Loss (%) | Intact (%) | Loss (%) | Intact (%) | Loss (%) | |
Curettage (n = 582) | 550 (94.7) | 31 (5.3) | 567 (97.5) | 14 (2.4) | 450 (79.4) | 117 (20.6) | 491 (84.4) | 91 (15.6) |
Hysterectomy (n = 753) | 709 (94.8) | 39 (5.2) | 730 (97.6) | 18 (2.4) | 566 (78.7) | 153 (21.3) | 609 (82.4) | 130 (17.6) |