Table 4 Prediction of poor disease-specific survival based on age, ER/PR and MSH6 protein expression in low-grade curettage specimens in endometrial cancer patients.

From: Mismatch repair markers in preoperative and operative endometrial cancer samples; expression concordance and prognostic value

Risk factor

N

Univariate HR (95% CI)

P

Multivariate HR (95% CI)

P

Age

432

1.1 (1.1–1.1)

<0.001

1.1 (1.0–1.1)

<0.001

ER/PR expressiona

 High

388

1

 

1

 

 Low

44

4.7 (2.6–9.0)

<0.001

4.4 (2.3–8.4)

<0.001

MSH6

 Low

264

1

 

1

 

 High

168

3.1 (1.7–5.7)

<0.001

2.9 (1.6–5.4)

<0.001

  1. MSH6 MutS Homolog 6.
  2. Statistically significant P-values (<0.05) are bold.
  3. aLow ER/PR expression, loss of or low expression of ER and loss of PR expression.
  4. Events; 46; Global P value (log-rank): <0.001.
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