Fig. 4: Survival outcome measures.

a Swimmer plot of 43 patients receiving an MTB-recommended therapy with available follow-up data. Blue bars indicate the duration of MTB-recommended therapy. b Comparison of the frequency of PFS2/1 ratios ≥1.3 and <1.3 between MTB-recommended and alternative therapies in evaluable patients. Progression-free survival (c) and overall survival (d) over the entire cohort comparing patients receiving MTB-recommended therapies, alternative therapies after the MTB, and patients without further therapies. Progression-free survival (e) and overall survival (f) achieved by tier m1A-based MTB therapies as opposed to all alternative non-MTB-recommended therapies. The P value was calculated by the log-rank test.