Table 1 Patient characteristics.

From: Critical evaluation of molecular tumour board outcomes following 2 years of clinical practice in a Comprehensive Cancer Centre

 

All patients

MTB therapy

Alternative therapy

P value

Population (n, %)

251 (100.00)

47 (18.73)

53 (21.12)

 

Mean age, standard deviation (years)

59 ± 12.00

56.19 ± 14.04

55.87 ± 11.69

0.7608a

Sex

   

0.6854b

 Male (n, %)

144 (57.37)

29 (61.7)

30 (56.7)

 

 Female (n, %)

107 (42.63)

18 (38.30)

23 (43.40)

 

ECOG PS at MTB

 0

62

14

15

>0.9999b

 1

55

13

13

>0.9999b

 2

4

0

1

>0.9999b

 5

8

0

0

 

Recommendations (n, %)

125 (49.80)

47 (100.00)

19 (35.85)

 

Evidence-level primary recommendation (n, %)

 m1A

30 (24.79)

17 (36.17)

1 (5.26)

0.0133b

 m1B

20 (16.53)

8 (17.39)

4 (21.05)

0.735b

 m1C

22 (18.18)

7 (15.22)

3 (15.79)

>0.9999b

 m2A

18 (14.88)

6 (12.77)

5 (26.32)

0.2753b

 m2B

6 (4.96)

1 (2.17)

1 (5.26)

0.5024b

 m2C

13 (10.74)

3 (6.38)

2 (10.53)

0.6208b

 m3

7 (5.79)

2 (4.35)

3 (15.79)

0.1444b

 m4

5 (4.13)

3 (6.52)

0 (0.00)

0.5498b

Previous lines (median, range)

2, 0–10

2, 0–6

2, 1–9

0.9166a

Entity (n, %)

 CRC

36 (14.40)

1 (2.13)

6 (11.11)

0.1182b

 iCCA

33 (13.20)

7 (14.89)

5 (9.26)

0.5395b

 PDAC

18 (7.20)

0 (0.00)

3 (5.56)

0.2461b

 Gastric Ca

16 (6.40)

5 (10.64)

3 (5.56)

0.4671b

 Sarcoma

14 (5.60)

6 (12.77)

5 (9.26)

0.7507b

 CUP

13 (5.20)

3 (6.38)

4 (7.41)

>0.9999b

 pCCA

10 (4.00)

3 (6.38)

0 (0.00)

0.0973b

 Breast Ca

10 (4.00)

0 (0.00)

3 (5.56)

0.2461b

 eCCA

9 (3.60)

2 (4.26)

3 (5.56)

>0.9999b

 Gallbladder Ca

8 (3.20)

2 (4.26)

0 (0.00)

0.2141b

 NSCLC

8 (3.20)

2 (4.26)

1 (1.85)

0.5964b

 Salivary gland Ca

8 (3.20)

3 (6.38)

2 (3.70)

0.6615b

 Urothelial Ca

7 (2.80)

1 (2.13)

4 (7.41)

0.3685b

 HNSCC

6 (2.40)

0 (0.00)

3 (5.56)

0.2461b

 HGSC

5 (2.00)

0 (0.00)

2 (3.70)

0.4974b

 Prostatic Ca

5 (2.00)

0 (0.00)

2 (3.70)

0.4974b

 Lymphoma

4 (1.60)

2 (4.26)

1 (1.85)

0.5964b

 Melanoma

4 (1.60)

1 (2.13)

0 (0.00)

0.4653b

 HCC

4 (1.60)

0 (0.00)

1 (1.85)

>0.9999b

 NEC

4 (1.60)

1 (2.13)

0 (0.00)

0.4653b

 Oesophageal Ca

4 (1.60)

0 (0.00)

2 (3.70)

0.4974b

Others (n ≤ 3 in all patients)

24 (9.60)

8 (17.02)

4 (7.41)

0.2169b

  1. The P values were calculated as follows (comparison MTB and Alternative therapy columns): aMann–Whitney U, bFisher’s exact test.