Table 1 Description of RSBCS programmes.

From: The cost-effectiveness of risk-stratified breast cancer screening in the UK

Regimen

Description of risk groupings

Screening programmes offered to woman in the risk groups

BRAID 1

(1) Breast imaging reporting and data system (BI-RADS) classification A&B or (2) BI-RADS classification C&D

(1) Triennial mammogram (MAM), or (2) additional 18-monthly automated ultrasound (AUS)

BRAID 2

(1) BI-RADS A&B or (2) BI-RADS C&D

(1) Triennial MAM, or (2) additional 18-monthly contrast-enhanced spectral MAM (CESM)

BRAID 3

(1) BI-RADS A&B or (2) BI-RADS C&D

(1) Triennial MAM, or (2) additional 18-monthly abbreviated Magnetic Resonance Imaging (AMRI)

ASSURE 1

(1) < 3.5% Tyrer–Cuzick (TC), (2) 3.5% - 8% TC or (3) > 8% TC

(1) Triennial MAM, (2) biennial MAM, or (3) annual MAM

ASSURE 2

(1) Lowest TC risk tertile, (2) middle TC tertile or (3) highest TC risk tertile

(1) Triennial MAM, (2) biennial MAM, or (3) annual MAM

ASSURE 3

(1) Volumetric Breast Density (VBD) 1 & 2, (2) VBD 3 & 4 or (3) VBD 3&4 and >8% TC

(1) Triennial MAM, (2) triennial MAM with handheld ultrasound (HUS), or (3) triennial MAM with MRI

ASSURE 4

(1) < 3.5% TC and VBD 1&2, (2) < 3.5% TC and VBD 3&4, (3) 3.5–8% TC and VBD 1&2, (4) 3.5–8% TC and VBD 3&4, (5) > 8% TC and VBD 1&2 or (6) > 8% TC and VBD 3&4

(1) Triennial MAM, (2) triennial MAM with HUS, (3) biennial MAM, (4) biennial MAM with HUS, (5) annual MAM, or (6) annual MAM with HUS

PROCAS

(1) Age 35–49 y and >2.5% TC, (2) age 45–49 y and >1.5% TC, (3) age 50 and above and < 1.5% TC, (4) age 50 and above and 1.5–2.5% TC, (5) age 50 and above and 2.5–5% TC or (6) age 50 and above and >5% TC

(1) Annual MAM to age 50, (2) annual MAM to age 50, (3) no screening, (4) triennial MAM, (5) biennial MAM, or (6) annual MAM

  1. BRAID Breast Screening Risk Adaptive Imaging for Density, ASSURE Adapting Breast Cancer Screening Strategy Using Personalised Risk Estimation, PROCAS Predicting Risk of Cancer at Screening, TC Tyrer–Cuzick, BI-RADS breast imaging reporting and data system, VBD volumetric breast density, MAM mammogram, AUS automated ultrasound, HUS handheld ultrasound, CESM contrast-enhanced spectral mammogram, AMRI abbreviated magnetic resonance imaging, MRI magnetic resonance imaging.