Fig. 3: Prevalence and odds ratio (OR) per standard deviation (SD) for the colorectal cancer (CRC) PRS for CRC and colorectal adenomas and among women (N = 254,618) and men (N = 199,115).
From: Genome-wide polygenic risk scores for colorectal cancer have implications for risk-based screening
The grey boxes represent the disease characteristic category. Total sample size N = 453,733. ORs were obtained from logistic regression models adjusted for sex, birth year, genotyping array, subcohort and the first ten genetic principal components of ancestry. Localised extent definition includes localised and locally advanced tumours. Non-localised extent definition includes tumours metastasised to local or distal lymph nodes and distant metastasis.
