Fig. 5: Spectrum of molecular signaling pathways in WT oncogenesis.
From: Cancer predisposition signaling in Beckwith-Wiedemann Syndrome drives Wilms tumor development
Both BWS-WT and altered-11p15 nonBWS-WT show enrichment of cell cycle pathways, DNA replication mechanisms and DNA repair mechanisms in addition to unique molecular pathways. Both BWS-WT and altered-11p15 nonBWS-WT exhibit unique SNVs.
