Table 2 GO term enrichment of differentially methylated probes in BWS-WT.
From: Cancer predisposition signaling in Beckwith-Wiedemann Syndrome drives Wilms tumor development
Ontology | Term | Total number of genes in term | Differentially methylated probes | P-value | FDR | |
|---|---|---|---|---|---|---|
GO:0198738 | BP | Cell-cell signaling by wnt | 455 | 316 | 9.39E–07 | 8.45E–05 |
GO:0016055 | BP | Wnt signaling pathway | 453 | 314 | 1.25E–06 | 0.00010898 |
GO:0035567 | BP | Non-canonical Wnt signaling pathway | 72 | 58 | 0.00022179 | 0.00900615 |
GO:0007229 | BP | Integrin-mediated signaling pathway | 113 | 87 | 0.00026507 | 0.01025539 |
GO:0007219 | BP | Notch signaling pathway | 181 | 126 | 0.0004182 | 0.01469345 |
GO:0030111 | BP | Regulation of Wnt signaling pathway | 333 | 227 | 0.00042077 | 0.01471591 |
GO:0008286 | BP | Insulin receptor signaling pathway | 122 | 88 | 0.00070441 | 0.02220243 |
GO:0046626 | BP | Regulation of insulin receptor signaling pathway | 72 | 54 | 0.0007045 | 0.02220243 |
GO:0030510 | BP | Regulation of BMP signaling pathway | 111 | 80 | 0.00117943 | 0.03309139 |
GO:0060070 | BP | Canonical Wnt signaling pathway | 307 | 206 | 0.00127743 | 0.03520494 |
