Table 3 GO Term enrichment of differentially methylated probes in altered-11p15 nonBWS-WT.
From: Cancer predisposition signaling in Beckwith-Wiedemann Syndrome drives Wilms tumor development
Ontology | Term | Total number of genes in term | Differentially methylated probes | P-value | FDR | |
|---|---|---|---|---|---|---|
GO:0000075 | BP | cell cycle checkpoint signaling | 186 | 119 | 5.98E–07 | 4.47E–05 |
GO:0000077 | BP | DNA damage checkpoint signaling | 121 | 80 | 1.10E–05 | 0.00066147 |
GO:0031570 | BP | DNA integrity checkpoint signaling | 129 | 84 | 1.43E–05 | 0.00083506 |
GO:1901988 | BP | negative regulation of cell cycle phase transition | 272 | 156 | 1.46E–05 | 0.00085117 |
GO:0043067 | BP | regulation of programmed cell death | 1508 | 755 | 9.05E–06 | 0.00056282 |
GO:0007093 | BP | mitotic cell cycle checkpoint signaling | 141 | 89 | 3.20E–05 | 0.0017054 |
GO:0038202 | BP | TORC1 signaling | 58 | 41 | 0.0001169 | 0.0054515 |
GO:0031929 | BP | TOR signaling | 127 | 80 | 0.00012544 | 0.00576725 |
GO:0097193 | BP | intrinsic apoptotic signaling pathway | 298 | 164 | 0.00056938 | 0.0209013 |
GO:0032006 | BP | regulation of TOR signaling | 105 | 65 | 0.00076791 | 0.02689792 |
GO:0016055 | BP | Wnt signaling pathway | 453 | 250 | 0.00114106 | 0.03708133 |
GO:0198738 | BP | cell-cell signaling by wnt | 455 | 251 | 0.00118165 | 0.0382377 |
GO:0031571 | BP | mitotic G1 DNA damage checkpoint signaling | 29 | 22 | 0.00155439 | 0.04698605 |
