Table 1 Multivariate Cox regression model for overall survival in the survival cohort with regard to AHRR and SFRP2 expression in the tumour cells and the TME.

From: AHRR and SFRP2 in primary versus recurrent high-grade serous ovarian carcinoma and their prognostic implication

AHRR

Tumour

TME

 

OS (n = 334)

OS (n = 334)

 Variable

HR

95% CI

p

HR

95% CI

p

 Age > 60

1.23

0.943–1.603

0.128

1.29

0.989–1.683

0,.060

 FIGO > II

2.68

1.187–6.067

0.018

2.59

1.146–5.870

0.022

 Residual tumour

2.01

1.526–2.639

<0.001

2.01

1.527–2.639

<0.001

 AHRR high

0.56

0.403–0.776

0.001

0.62

0.469–0.805

<0.001

SFRP2

 

OS (n = 316)

   

 Variable

HR

95% CI

p

   

 Age > 60

1.23

0.937–1.620

0.136

   

 FIGO > II

2.40

1.059–5.420

0.036

   

 Residual tumour

2.11

1.593–2.799

<0.001

   

 SFRP2 high

2.57

2.566–1.499

0.001

   
  1. TME tumour microenvironment, OS overall survival, n number of patients, HR hazard ratio, CI confidence interval, FIGO Fédération Internationale de Gynécologie et d’Obstretique. Bold values indicate statistical significance p < 0.05.
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