Fig. 3: GSTM3 potentiates the radiosensitivity of NPC cells in vivo. | British Journal of Cancer

Fig. 3: GSTM3 potentiates the radiosensitivity of NPC cells in vivo.

From: GSTM3 enhances radiosensitivity of nasopharyngeal carcinoma by promoting radiation-induced ferroptosis through USP14/FASN axis and GPX4

Fig. 3

a Schematic diagram of treatment procedure in subcutaneous tumour xenograft models. The 5-8F cells stably transfected with GSTM3 or empty vector lentivirus were used to construct subcutaneous tumour xenograft models. b The weights of the mice from each group were measured every two days. c–e Macroscopic images (c), volume (d), and weight (e) of the 5-8F xenograft tumours for each group (n = 4). f–h Representative IHC images (f) and staining scores of GSTM3 (g) and 4-HNE (h) of subcutaneous tumours from each group. Scale bars: 50 μm/20 μm. Data are presented as mean ± SEM. p values were calculated using two-tailed Student’s t test and two-way ANOVA. *p < 0.05; **p < 0.01; ***p < 0.001.

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