Fig. 2: Validation of TLS induction following immunotherapy.
From: Synergistic induction of tertiary lymphoid structures by chemoimmunotherapy in bladder cancer
a Comparison of GSVA scores utilizing four TLS signatures in 43 paired pre-ICI and post-ICI samples from GSE91061. b Comparison of GSVA scores utilizing four TLS signatures in pre-ICI and post-ICI samples from GSE115821. c Systematic evlauation of TLS maturity using H&E staining and multiplex IHC of CD20, CD21, CD23, CD3, Ki67 and PanCK. d Comparison of TLS positivity between pre-ICI and post-ICI samples in the RJBLC-I2N003 cohort. e Comparison of TLS maturity between pre-ICI and post-ICI samples in the RJBLC-I2N003 cohort.
